FDA letter asks veterinarians to discontinue use of unapproved aspirin products

By Gustavo Schuenemann, Department of Veterinary Preventive Medicine, The Oho State University

The U.S. Food and Drug Administration (FDA) recently published a “Dear Veterinarian Letter” informing veterinarians and their clients to discontinue use of unapproved aspirin products to treat pyrexia and pain in lactating dairy cattle. A total of 616 confirmed dairy herds in 15 U.S. states were reported positive for highly pathogenic avian influenza (HPAI) as of Nov. 22, 2024. Aspirin is a nonsteroidal anti-inflammatory drug (NSAID) that is being used on some dairy farms to treat cattle infected with HPAI. In the past, FDA considered aspirin products to be of low regulatory concern. However, because the increased use of unapproved aspirin and the availability in the U.S. market of labeled products for treatment of pyrexia (fever) in cattle, the FDA has shifted this stance to state such use as illegal.

The letter states that “The U.S. Food and Drug Administration understands that veterinarians and dairy farmers may be treating lactating dairy cattle for pyrexia and pain with aspirin and wants to clarify that there are no FDA-approved aspirin products for use in cattle.”… Continue reading